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Paracrystalline inclusions in Mycobacterium leprae
Annales De Microbiologie
|January 1, 1981
Summary
Electron microscopy revealed paracrystalline inclusions in Mycobacterium leprae, associated with intracellular membranes. These structures formed in leprosy bacilli infected with mycobacteriophage D29 or treated with mitomycin C.
Area of Science:
- Microbiology
- Cell Biology
- Electron Microscopy
Background:
- Paracrystalline inclusions in Mycobacterium leprae have been previously reported.
- These inclusions were observed in leprosy bacilli infected with mycobacteriophage D29 or treated with mitomycin C.
Purpose of the Study:
- To further describe the paracrystalline inclusions in Mycobacterium leprae.
- To investigate the association of these inclusions with intracellular structures.
Main Methods:
- Electron micrography was used to document paracrystalline inclusions.
- Leprosy bacilli were infected with mycobacteriophage D29 or treated with mitomycin C.
Main Results:
- Paracrystalline inclusions were observed in Mycobacterium leprae.
- These inclusions appeared to form in association with intracellular membranous structures within the bacilli.
Conclusions:
- The study provides further detailed documentation of paracrystalline inclusions in Mycobacterium leprae.
- The findings suggest a specific formation mechanism linked to intracellular membranes in leprosy bacilli.