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Updated: Aug 19, 2026

RNA Interference in Ticks
Published on: January 20, 2011
Biochemical mechanisms causing tick resistance
Abstract:
Three general biochemical mechanisms can cause ticks to be resistant to acaricides: an alteration in the properties of the site of action, a change in the rate of transportation and a change in the rate of metabolism. The first mechanism enables increased concentrations of acaricide at the site of action to be tolerated, while the last two mechanisms result in a decreased concentration and/or persistence of the acaricide at the site of action. These mechanisms are discussed in detail with reference to a range or acaricides, particular emphasis being given to blue tick strains occurring in Southern Africa.
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