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Carprofen in soft-tissue rheumatism. A controlled trial
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
|September 5, 1981
Summary
Carprofen and indomethacin showed equal efficacy in treating extra-articular inflammatory conditions. Carprofen was well-tolerated at 300 mg/day, demonstrating good results comparable to indomethacin.
Area of Science:
- Pharmacology
- Clinical Medicine
- Rheumatology
Background:
- Extra-articular inflammatory processes require effective and well-tolerated treatments.
- Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for inflammatory conditions.
Purpose of the Study:
- To compare the efficacy and tolerability of carprofen and indomethacin in patients with extra-articular inflammatory processes.
Main Methods:
- A randomized, double-blind clinical trial was conducted.
- Patients received either carprofen (300 mg/day) or indomethacin (75 mg/day) for 7 days.
Main Results:
- Both carprofen and indomethacin demonstrated good efficacy.
- Carprofen's efficacy was found to be equal to that of indomethacin.
- Carprofen was generally well-tolerated at the tested dosage.
Conclusions:
- Carprofen is an effective and well-tolerated option for managing extra-articular inflammatory processes.
- Carprofen offers comparable therapeutic benefits to indomethacin for these conditions.