[Ackerman's verrucous carcinoma on the lower lip]

Area of Science:

• Oral Pathology
• Dermatology
• Oncology

Background:

• Ackerman's verrucous carcinoma (AVC) is a rare, low-grade variant of squamous cell carcinoma.
• AVC typically occurs on the lower extremities and oral mucosa, but not previously reported on the lower lip's transitional epithelium.

Observation:

• A unique case of AVC is presented, specifically located on the transitional epithelium of a patient's lower lip.
• The clinical presentation and progression mirrored that of AVC in other anatomical sites.
• Ultrastructural examination did not reveal the presence of viral particles.

Findings:

• The patient's Ackerman's verrucous carcinoma presented in an unprecedented location on the lower lip's transitional epithelium.
• The clinical behavior was consistent with verrucous carcinoma found elsewhere.
• No viral etiology was identified through ultrastructural analysis.

Implications:

• This case expands the known anatomical distribution of Ackerman's verrucous carcinoma.
• It highlights the importance of considering AVC in lower lip lesions with a verrucous appearance.
• Conservative surgical management appears effective for this rare presentation.