Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A screening test for assessing iron status

J Pintar, B S Skikne, J D Cook

    Blood
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    A new, rapid ferritin test can detect iron overload in developing countries, preventing complications from anemia interventions in individuals with hemoglobin synthesis defects. This simple blood test aids in population screening for iron status.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Identifying subtypes of Hypersomnolence Disorder: a clustering analysis.

    Sleep medicine·2019
    Same author

    Ductal Plate Malformation in the Liver of Boxer Dogs: Clinical and Histological Features.

    Veterinary pathology·2016
    Same author

    Effects of oral temazepam on slow waves during non-rapid eye movement sleep in healthy young adults: A high-density EEG investigation.

    International journal of psychophysiology : official journal of the International Organization of Psychophysiology·2016
    Same author

    Effects of oral temazepam on sleep spindles during non-rapid eye movement sleep: A high-density EEG investigation.

    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology·2015
    Same author

    Abdominal Ultrasound Examination Findings in 534 Hyperthyroid Cats Referred for Radioiodine Treatment Between 2007-2010.

    Journal of veterinary internal medicine·2015
    Same author

    Mechanism of thrombocytopenia in chronic hepatitis C as evaluated by the immature platelet fraction.

    International journal of laboratory hematology·2012
    Same journal

    Fibrocytes drive JAK2V617F-mutated myelofibrosis: pitavastatin reverses marrow fibrosis and anemia.

    Blood·2026
    Same journal

    Identifying steroid-refractory aGVHD before it happens.

    Blood·2026
    Same journal

    ELISA-negative HIT: antibody recognition and relevance.

    Blood·2026
    Same journal

    EBV and immunodeficiency: the odd couple drawn to the brain.

    Blood·2026
    Same journal

    A bone to pick with ferric carboxymaltose.

    Blood·2026
    Same journal

    A step toward streamlining HIT diagnosis.

    Blood·2026
    See all related articles

    Area of Science:

    • Biochemistry
    • Hematology
    • Public Health

    Background:

    • Iron deficiency anemia interventions in developing nations may exacerbate iron overload in individuals with inherited hemoglobin synthesis defects.
    • Accurate and rapid detection of iron overload is crucial for population screening programs to mitigate this risk.

    Purpose of the Study:

    • To develop a fast and simple method for detecting iron overload in population screening settings.
    • To provide a tool that can distinguish iron deficiency from iron overload.

    Main Methods:

    • A modified two-site enzyme-linked immunoassay was developed for semiquantitative ferritin measurement.
    • The assay utilizes only two drops of whole blood with a 90-minute incubation period.

    Main Results:

    Related Experiment Videos

    • The developed method provides a rapid and simple assessment of iron status.
    • The assay effectively differentiates between iron deficiency and even mild increases in storage iron.

    Conclusions:

    • This ferritin measurement assay has broad applicability for prompt iron status assessment in resource-limited settings.
    • The method can help prevent iatrogenic iron overload in vulnerable populations undergoing anemia treatment.