Deposition of complement C1q in primary localized cutaneous amyloidosis

Deposition of immunoglobulins and complement components was studied in twelve cases of primary localized cutaneous amyloidosis by direct immunofluorescence microscopy. C1q was detected in amyloid islands in ten cases by immunoglobulins and C3 were found in only a few cases. It is suggested that C1q may be one of the nonepidermal components of cutaneous amyloid.