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Sensorineural hearing loss and somatic insufficiency

O Bentzen

    Audiology : Official Organ of the International Society of Audiology
    |January 1, 1982
    PubMed
    Summary
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    Otosclerosis is a systemic disease affecting ectomesodermal tissues, not just the ear. Corneometry, measuring corneal thickness, helps diagnose this somatic insufficiency in at-risk individuals.

    Area of Science:

    • Otolaryngology
    • Genetics
    • Dermatology

    Background:

    • Otosclerosis is often viewed as an isolated ear disorder, but evidence suggests broader systemic involvement.
    • Subclinical manifestations in hair, nails, joints, and teeth are observed in otosclerosis patients.
    • Ectomesodermal insufficiency, a systemic condition, is hypothesized as the underlying cause of otosclerosis.

    Observation:

    • Light microscopy reveals ground substance metachromasia and collagen/elastic fiber abnormalities in the skin of otosclerosis patients.
    • Corneometry, an objective method, measures corneal thickness to assess somatic insufficiency.
    • A high prevalence of abnormal corneal thickness ('cornea-positive') is noted in otosclerosis patients.

    Findings:

    • Otosclerosis is characterized by ectomesodermal insufficiency, a universal somatic insufficiency.

    Related Experiment Videos

  • Corneometry identifies 'cornea-positive' individuals, indicating abnormal corneal thickness.
  • Sensorineural hearing loss and noise-induced hearing impairment cases can also be 'cornea-positive', suggesting reduced auditory resistance.

    • Implications:

    • Corneometry serves as a valuable diagnostic tool for identifying individuals with an insufficient somatic constitution.
    • Early diagnosis of somatic insufficiency can help identify individuals at risk for hearing disorders.
    • This research broadens the understanding of otosclerosis as a systemic condition, impacting multiple ectomesodermal tissues.