Effect of gonadotrophin releasing hormone in underfed immature rats

An investigation on the effect of restricted feeding an GnRH treatment using immature rats of both sexes was made to see if the GnRH can produce its desired effect on the reproductive organs through the pituitary gonadal axis irrespective of the age and nutritional status of the animal. It was observed that immature male and female rats responded differently to the treatment of GnRH and responses are to a great extent age-dependent. Restricted feeding in these animals slowed down the growth of the reproductive organs.