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Related Experiment Videos

[Coagulometer H21: an automatic apparatus for coagulation study (author's transl)]

J Guimbretière, D Boudart

    Nouvelle Revue Francaise D'Hematologie
    |June 10, 1978
    PubMed
    Summary

    A new automated device accurately measures plasma clotting time by detecting solution-to-gel transformation. This device performs 50 tests without manual intervention, ensuring high precision and preventing contamination for reliable results.

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    Presse medicale (Paris, France : 1983)·1993

    Area of Science:

    • Biomedical Engineering
    • Clinical Chemistry
    • Hematology

    Context:

    • Accurate measurement of clotting time is crucial for diagnosing and monitoring coagulation disorders.
    • Manual methods for clotting time analysis are labor-intensive and prone to variability.
    • Existing automated systems may have limitations in throughput or contamination control.

    Purpose:

    • To introduce a novel automated device for precise plasma clotting time measurement.
    • To automate the process of plasma and reagent handling, clotting time recording, and data processing.
    • To minimize contamination risks through the use of disposable components.

    Summary:

    • The device automatically dispenses plasma and reagents, records the transformation time from solution to gel, and processes data.
    • It is capable of performing up to 50 tests autonomously.
    • Disposable tubing and sample plates ensure a contamination-free analysis, enhancing result reliability.

    Impact:

    • Achieves accuracy superior to manual methods, with a coefficient of variation below 3%.
    • Increases laboratory efficiency and reduces the potential for human error in clotting time assays.
    • Provides a reliable and efficient tool for clinical laboratories involved in hemostasis testing.

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