[Cholera vibrio culture in a fermenter with automatic control of a number of parameters]

The cultivation of V. cholerae was carried out in casein broth in a fermenter. 2 kinds of cultivation conditions were compared. The results thus obtained indicate that the cultivation of V. cholerae under the conditions of the controlled level of dissolved oxygen (pO2--50%) ensures the optimum conditions for proliferation and the high yield of biomass; it also allows obtaining vaccine whose immunogenic properties are not inferior to those of the WHO reference vaccine.