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Does ATP cross the cell plasma membrane

The Yale Journal of Biology and Medicine

|January 1, 1982

Summary

This summary is machine-generated.

Cells can release and take up adenosine triphosphate (ATP), a key energy molecule. This review highlights evidence that ATP can indeed cross cell membranes, challenging previous assumptions and indicating these are normal physiological processes.

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Area of Science:

Cell Biology
Biochemistry
Physiology

Background:

The transport of adenosine triphosphate (ATP) across cell membranes has been a subject of debate.
Prevailing views suggested that ATP, a crucial cellular energy currency, could not permeate the cell membrane.

Purpose of the Study:

To review and consolidate evidence regarding the release and uptake of ATP by cells.
To address the prevailing concept that ATP cannot cross the cell membrane.

Main Methods:

Literature review of studies investigating cellular ATP transport.
Analysis of experimental data from various investigators on ATP release and uptake.

Main Results:

The reviewed evidence strongly indicates that ATP can cross the cell membrane.

Related Experiment Videos

Multiple studies support the bidirectional movement of ATP into and out of cells.

Conclusions:

The release and uptake of ATP by cells are physiological processes.
The ability of ATP to cross cell membranes is supported by substantial scientific evidence.