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Malakoplakia of palatine tonsil
American Journal of Clinical Pathology
|September 1, 1982
Summary
This study documents a rare case of unilateral tonsillar malakoplakia, a condition linked to Escherichia coli infection. Antibiotic treatment led to lesion resolution, marked by specific histological changes including increased Michaelis-Gutmann bodies.
Area of Science:
- Pathology
- Microbiology
- Otolaryngology
Background:
- Malakoplakia is a rare chronic inflammatory condition.
- Unilateral tonsillar involvement is exceptionally uncommon.
- Escherichia coli is a potential causative agent.
Observation:
- A case of unilateral tonsillar malakoplakia is presented.
- Repeated cultures identified Escherichia coli with normal biologic properties.
- The lesion was monitored via punch biopsies before and after treatment.
Findings:
- Histological examination post-antibiotic therapy showed resolution of edema, granulocytes, and bacilli.
- A notable increase in Michaelis-Gutmann (MG) bodies and calcified particles was observed during healing.
- Foamy plasma cells increased before the lesion's eventual resolution.
Implications:
- This case contributes to understanding malakoplakia pathogenesis.
- Highlights the role of Escherichia coli in tonsillar malakoplakia.
- Demonstrates effective antibiotic treatment for this rare condition.