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Related Experiment Videos

'Long-loop' reflexes can be obtained in spinal monkeys

D J Tracey, B Walmsley, J Brinkman

    Neuroscience Letters
    |May 15, 1980
    PubMed
    Summary

    Muscle stretch responses in cats and monkeys reveal that supraspinal centers are not essential for generating longer latency electromyogram peaks (M2). This finding impacts our understanding of motor control pathways.

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    Area of Science:

    • Neuroscience
    • Motor Control
    • Physiology

    Background:

    • Muscle stretch reflexes involve complex neural pathways.
    • The M1 and M2 peaks in electromyograms represent different components of these responses.
    • The role of supraspinal centers in generating the M2 component has been debated.

    Purpose of the Study:

    • To investigate the neural circuitry underlying the M2 component of the electromyographic response to muscle stretch.
    • To determine if supraspinal centers, such as the cerebral cortex and cerebellum, are necessary for the M2 response.

    Main Methods:

    • Electromyograms were recorded from extensor muscles in anesthetized monkeys (Macaca fascicularis) and cats during limb stretching.
    • Spinal cord transection was performed at a high cervical level to isolate spinal pathways.
    • Analysis focused on the presence and characteristics of M1 and M2 peaks before and after spinalization.

    Main Results:

    • Both short (M1) and longer latency (M2) electromyogram peaks were observed following muscle stretch.
    • After high cervical spinal section, both M1 and M2 peaks persisted, although with reduced amplitude.
    • The M2 peak's presence after spinalization indicates it does not solely rely on descending input from the brain.

    Conclusions:

    • The cerebral cortex and cerebellum are not essential components of the neural circuitry generating the longer latency (M2) electromyographic response to muscle stretch.
    • These findings suggest that supraspinal centers are not required for the M2 response, implicating other neural pathways.

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