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[Ocular herpes simplex in children (author's transl)]

J Colin, M Le Grignou, A Le Grignou

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1982
    PubMed
    Summary

    Ocular herpes simplex in children frequently recurs, leading to significant vision loss. All children experienced recurrences within 2 years, with many facing poor visual acuity long-term.

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    Area of Science:

    • Ophthalmology
    • Virology
    • Pediatrics

    Context:

    • Ocular herpes simplex virus (HSV) infection is a significant concern in pediatric populations.
    • Recurrent ocular HSV infections can lead to chronic visual impairment.

    Purpose:

    • To report on the long-term outcomes of ocular herpes simplex infections in a cohort of 38 children.
    • To analyze recurrence rates and visual acuity following initial ocular HSV diagnosis.

    Summary:

    • The study followed 38 children with ocular HSV for 1-10 years, with primary infections occurring between ages 2-6.
    • Recurrences increased with follow-up duration; 50% recurred within 2 years, and 100% recurred after 2 years.
    • Idoxuridine treatment failed in 11 cases of superficial keratitis. After 5 years, 75% had visual acuity of 5/10 or less.

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    Impact:

    • Ocular herpes simplex is a leading cause of vision loss and disability in children.
    • Findings highlight the chronic and progressive nature of pediatric ocular HSV, underscoring the need for effective management strategies.
    • The high rate of visual impairment emphasizes the importance of early diagnosis and intervention to preserve vision in affected children.