Evaluation of rapid colonoscopy preparation using a new gut lavage solution

The traditional colonoscopy preparation of laxatives and enemas requires 2 days to complete and is occasionally unsatisfactory. The alternative method, gut lavage with saline-based solutions, is hazardous in elderly or compromised patients because of overhydration. We studied a new, orally ingested electrolyte solution containing sodium sulfate and polyethylene glycol as preparation for elective colonoscopy in a consecutive series of 43 patients. Almost all patients achieved a good to excellent preparation. There were no changes in fluid or electrolyte balance and no complications of the procedure. Colonoscopy preparation with this technique is rapid, effective, and well tolerated and is a safe alternative to the standard approach.