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5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
The evolution of renal function after surgical treatment of malignant lithiasis with severely compromised renal
Abstract:
16 patients with calcic nephrolithiasis and renal failure were admitted to our institute and underwent surgery. 4 patients had bilateral nephrolithiasis and 12 cases had relapsed. Selective nephrotomy was performed in all cases, pyelotomy was done in 8 and partial nephrectomy in 2 patients. In 8 patients renal function improved but no difference was observed in 6 patients. Renal function worsened in 2 patients who had shown significant preoperative proteinuria. According to our experience, the success of this therapy depends on: (1) accurate patient selection; (2) adequate preoperative treatment, and (3) personalization of surgical management.
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