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Tear calcium levels in normal subjects

J A Caldeira, W W Luthold, E Sabbaga

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1982
    PubMed
    Summary
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    Tear calcium levels in normal subjects show no significant age-related differences. The average tear calcium concentration is 4.40 mg/100 ml, representing about 45.68% of serum calcium.

    Area of Science:

    • Ophthalmology
    • Biochemistry
    • Human Physiology

    Background:

    • Calcium is crucial for various physiological processes.
    • Understanding tear calcium levels is important for ocular health assessment.
    • Previous research has not extensively detailed tear calcium concentrations across different age groups.

    Purpose of the Study:

    • To determine tear calcium content in healthy individuals.
    • To investigate potential age-related variations in tear calcium levels.
    • To compare tear calcium levels with serum calcium concentrations.

    Main Methods:

    • Tear samples were collected from 30 healthy adult subjects.
    • Subjects were divided into six age groups (2nd to 7th decade).
    • Calcium concentration in tears was measured and compared to serum calcium.

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    Main Results:

    • No statistically significant differences in tear calcium content were observed across the age groups.
    • The mean tear calcium concentration was 4.40 mg/100 ml (SD 1.22).
    • Tear calcium constituted approximately 45.68% of serum calcium, consistent across all groups.

    Conclusions:

    • Tear calcium levels are relatively stable and not significantly affected by age in healthy adults.
    • The ratio of tear calcium to serum calcium is consistent and may reflect serum ionized calcium levels.
    • These findings provide a baseline for tear calcium concentration in normal populations.