Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nuclear techniques in ischemic heart disease

H N Wagner

    American Heart Journal
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Radioactive tracer techniques now allow precise measurement of cardiac function, including ventricular volume changes. This improves assessment of drug effects on myocardial contraction in complex heart diseases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Positron emission tomography of 5-HT transporter sites in the baboon brain with [11C]McN5652.

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·1995
    Same author

    A new era of certainty.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·1995
    Same author

    Intrastriatal dopamine infusion reverses compensatory increases in D2-dopamine receptors in the 6-OHDA lesioned rat.

    Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration·1995
    Same author

    Molecular nuclear medicine: from genotype to phenotype via chemotype.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·1995
    Same author

    In vivo D2 dopamine receptor density in psychotic and nonpsychotic patients with bipolar disorder.

    Archives of general psychiatry·1995
    Same author

    An improved method for the synthesis of radiolabeled McN5652 via thioester precursors.

    Nuclear medicine and biology·1995
    Same journal

    Stratified Medicine with Eplerenone for Myocardial Infarction or Injury and No obstructive Coronary Arteries: A Registry-Based Basket Trial.

    American heart journal·2026
    Same journal

    Revised Lipid-Lowering Therapy Guidelines in a Nationally Representative Sample.

    American heart journal·2026
    Same journal

    Cardiometabolic Health of Low- and Higher-Income Adults in the United States, 2009-2023.

    American heart journal·2026
    Same journal

    Moving Beyond Technical Capability to Regulatory Integration for Digital Health Technology Devices-Brief Communication from the Cardiovascular Sciences Research Consortium.

    American heart journal·2026
    Same journal

    THE SOCIETY OF CRITICAL CARE CARDIOLOGY - RATIONALE, BLUEPRINT, AND LESSONS LEARNED IN THE CREATION OF A NEW MULTIDISCIPLINARY PROFESSIONAL ORGANIZATION.

    American heart journal·2026
    Same journal

    DOAC Score Among Patients Receiving Vitamin K Antagonists.

    American heart journal·2026
    See all related articles

    Area of Science:

    • Cardiology
    • Nuclear Medicine
    • Pharmacology

    Background:

    • Assessing myocardial contraction (inotropic effect) traditionally required invasive ventricular pressure measurements.
    • Cardiac output measurements are limited as they depend on multiple factors beyond contractile state.

    Purpose of the Study:

    • To introduce and detail the application of radioactive tracer techniques for evaluating cardiac function.
    • To demonstrate the utility of these techniques in assessing drug responses in patients with complex cardiac conditions.

    Main Methods:

    • Utilized radioactive tracer techniques to measure dynamic changes in ventricular volume throughout the cardiac cycle.
    • Enabled measurement of end-diastolic volume, end-systolic volume, ejection fraction, and timing intervals.

    Related Experiment Videos

    Main Results:

    • Radioactive tracer techniques provide comprehensive data on ventricular dynamics.
    • Accurate assessment of ventricular emptying and filling rates is now feasible.

    Conclusions:

    • Radioactive tracer techniques offer a non-invasive and detailed method for assessing cardiac contractility and drug efficacy.
    • This advancement is particularly valuable for managing patients with combined valvular and coronary artery disease.