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[NAG vibrio sensitivity to antibiotics]
Abstract:
Sensitivity of 575 NAG-vibrio strains isolated from various substrates in 1978-1980 to 14 antibiotics was studied and compared with the results of an analogous study performed in 1968 by Z. V. Ermolyeva et al. It was shown that sensitivity of NAG-vibrio to chloramphenicol, ampicillin, cephaloridine and streptomycin decreased. However, NAG-vibrio remain to be sensitive to tetracycline, chloramphenicol and gentamicin. Resistance of the majority of the strains to ampicillin, carbenicillin, cephaloridine and polymyxin M was noted.
Insights
Antibiotic resistance in NAG-vibrio strains has increased since 1968, with decreased sensitivity to several key antibiotics. However, these bacteria remain sensitive to tetracycline, chloramphenicol, and gentamicin.
Area of Science:
- Microbiology
- Infectious Diseases
- Pharmacology
Background:
- NAG-vibrio (non-agglutinable Vibrio) are significant environmental bacteria.
- Antibiotic resistance patterns in bacteria are dynamic and require continuous monitoring.
- Previous studies have established baseline antibiotic sensitivities for NAG-vibrio.
Purpose of the Study:
- To assess the current antibiotic sensitivity profile of NAG-vibrio strains.
- To compare contemporary sensitivity data with historical data from 1968.
- To identify trends in antibiotic resistance in NAG-vibrio.
Main Methods:
- Isolation and identification of 575 NAG-vibrio strains from diverse substrates between 1978-1980.
- Antimicrobial susceptibility testing of isolates against 14 different antibiotics.
- Comparative analysis with antibiotic sensitivity data from a 1968 study.
Main Results:
- A significant decrease in NAG-vibrio sensitivity was observed for chloramphenicol, ampicillin, cephaloridine, and streptomycin compared to 1968.
- The majority of strains exhibited resistance to ampicillin, carbenicillin, cephaloridine, and polymyxin M.
- NAG-vibrio strains maintained sensitivity to tetracycline, chloramphenicol, and gentamicin.
Conclusions:
- There has been a concerning increase in antibiotic resistance among NAG-vibrio strains over a decade.
- Monitoring antibiotic resistance trends is crucial for effective treatment strategies.
- Certain antibiotics like tetracycline, chloramphenicol, and gentamicin remain effective against NAG-vibrio.