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Prostatic carcinoma metastatic to choroid
The British Journal of Ophthalmology
|April 1, 1982
Summary
Hormonal therapy, including orchidectomy and estrogen, effectively treated metastatic prostate cancer in the choroid. This approach led to tumor regression and vision restoration, establishing it as a preferred initial treatment.
Area of Science:
- Ophthalmology
- Oncology
- Endocrinology
Background:
- Prostatic carcinoma can metastasize to the choroid, potentially causing significant vision loss.
- Metastatic choroidal tumors present a therapeutic challenge in advanced prostate cancer management.
Observation:
- A patient with metastatic prostatic carcinoma of the choroid received orchidectomy and estrogen therapy.
- Close monitoring revealed a rapid regression of the choroidal tumor over two months.
Findings:
- The choroidal tumor became clinically undetectable following hormonal manipulation.
- Significant visual improvement was observed, with visual acuity returning to 6/6 from 6/60, and visual field was restored.
Implications:
- Hormonal manipulation demonstrates a dramatic and effective response in treating choroidal metastases from prostate cancer.
- The lack of complications associated with this therapy supports its role as a preferred initial treatment modality.