Related Experiment Videos
[Hepatitis caused by Campylobacter coli (author's transl)]
La Nouvelle Presse Medicale
|February 20, 1982
Summary
Campylobacter coli, a bacterium usually causing enterocolitis, was identified as the cause of hepatitis in a patient. Antibiotic treatment led to a full recovery, suggesting a novel link between this bacterium and liver inflammation.
Area of Science:
- Hepatology
- Infectious Diseases
- Microbiology
Background:
- Campylobacter coli is a recognized cause of gastrointestinal infections, specifically ulcerous enterocolitis.
- Hepatitis has not been previously reported as a clinical manifestation of Campylobacter coli infection.
Observation:
- A 50-year-old woman presented with symptoms including diarrhea, fever, malaise, jaundice, and hepatomegaly.
- The patient had no prior history of liver disease.
Findings:
- Haemoculture confirmed the presence of Campylobacter coli.
- Liver biopsies revealed necrosis and polymorphonuclear infiltrates.
- Biochemical tests and liver size normalized following antibiotic therapy.
- Other potential causes of acute or chronic liver disease were ruled out.
Implications:
- This case suggests Campylobacter coli can cause hepatitis.
- Successful antibiotic treatment highlights the importance of considering this pathogen in unexplained hepatitis.
- Further research is warranted to understand the mechanism of Campylobacter coli-induced hepatitis.