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Related Experiment Videos

Filamentary keratitis

W Hamilton, T O Wood

    American Journal of Ophthalmology
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Five percent sodium chloride eyedrops effectively treated filamentary keratitis in most patients. This common eye condition, often linked to corneal diseases, showed significant improvement with this hypertonic saline treatment.

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    Area of Science:

    • Ophthalmology
    • Corneal Diseases
    • Ocular Surface Disease

    Background:

    • Filamentary keratitis is a condition characterized by the formation of mucus filaments on the corneal surface.
    • It is often associated with underlying ocular surface diseases, including keratoconjunctivitis sicca and corneal trauma.
    • Effective treatment strategies for filamentary keratitis are crucial for patient comfort and visual recovery.

    Purpose of the Study:

    • To evaluate the efficacy of 5% sodium chloride (hypertonic saline) eyedrops in treating filamentary keratitis.
    • To determine the response rate and time to resolution in patients with filamentary keratitis associated with various underlying conditions.

    Main Methods:

    • A prospective study involving 16 patients (19 eyes) diagnosed with filamentary keratitis.

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  • Treatment consisted of 5% sodium chloride eyedrops administered three to four times daily.
  • Patient outcomes were monitored for resolution of filaments, symptoms, and signs.

    • Main Results:

    • An overall success rate of 95% (18 of 19 eyes) was achieved.
    • Filaments associated with acute or traumatic corneal diseases resolved rapidly, typically within one week.
    • Cases related to keratoconjunctivitis sicca showed a slower response (average four weeks), with one failure (11%).
    • Essential filamentary keratitis also responded within four weeks.

    Conclusions:

    • 5% sodium chloride eyedrops are a highly effective treatment for filamentary keratitis across various etiologies.
    • Rapid resolution is observed in cases linked to acute or traumatic corneal conditions.
    • While effective for most, a small percentage of patients with keratoconjunctivitis sicca may not respond to this treatment.