Related Experiment Video
Updated: Aug 14, 2026

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Published on: February 22, 2011
Some physiological consequences of the rapid smoking treatment for cigarette addiction
Abstract:
The effects of rapid smoking, casual smoking, and rapid breathing on heart rate, blood pressure, cardiac output, and rectal-forearm-finger temperatures were compared. Carboxyhemoglobin, end-tidal carbon monoxide, plasma nicotine, electrocardiogram, and subjective symptom data were also obtained during these conditions as an older subject group smoked low nicotine cigarettes and younger subject groups smoked either high or low nicotine cigarettes. The authors concluded that the physiological changes produced by rapid smoking are greater than those produced by casual smoking and are not an artifact of rapid breathing. The controversy concerning the hazard potential of rapid smoking for either young or older subjects, however, is not fully resolved.
Related Concept Videos
Drug Dependence
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
CNS Depressants: Alcohol and Nicotine
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Stress Prevention and Stress Management Techniques IV

