Colon cancer in a low-risk population

Area of Science:

• Epidemiology
• Cancer Research
• Public Health

Background:

• Colon cancer mortality rates in Utah were examined.
• Previous studies suggested potential geographic variations in cancer incidence.

Purpose of the Study:

• To investigate colon cancer mortality and incidence in Utah.
• To compare Utah's rates with national averages.
• To explore potential contributing factors, including lifestyle and diet.

Main Methods:

• Analysis of mortality data from 1950-1969.
• Incidence data collection for 1966-1970.
• Comparison of Utah population (including Mormons) with U.S. averages.
• Preliminary dietary survey.

Main Results:

• Utah had 34% fewer colon cancer deaths than the U.S. average (1950-1969).
• Colon cancer incidence was 37% lower in Utah Mormons and 18% lower in non-Mormons compared to the U.S. average (1966-1970).
• Dietary factors (meat, fat, fiber) showed minimal differences between Utah and the U.S.

Conclusions:

• Utah exhibits lower colon cancer mortality and incidence compared to the U.S. average.
• Lifestyle factors, particularly tobacco and alcohol abstinence among Mormons, may play a significant role.
• Dietary habits do not appear to be the primary differentiating factor for lower rates in Utah.