[Magnetic sedimentation of protein molecules]

Usage of pondermotive interaction of protein molecules with heterogenous magnetic field for the studies of their physico-chemical properties is considered. Possibility is shown of creating spatial heterogenous concentration of macromolecules whose value is close to the equilibrium one near the slit edge of the magnetic system. Potentialities of magnetic sedimentation of macromolecules are compared with different variants of centrifugation. It is shown that by means of magnetic sedimentation the data on the shape, volume and molecular weight of the molecules, as well as on the change of these parameters, can be obtained. It is also possible to calculate the distribution parameters of macromolecules according to their magnetic sensitivity and partial volumes and to find correlation between these parameters. Conduction of macromolecule sedimentation in the media with different magnetic sensitivity allows to enlarge the scope of the information obtained.