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Crohn's disease in Barrett's esophagus
The American Journal of Gastroenterology
|June 1, 1978
Summary
This case report details a patient with Crohn's disease who developed a benign esophageal stricture and Barrett's esophagus, a rare combination. This finding highlights the potential esophageal manifestations of Crohn's disease.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Crohn's disease, an inflammatory bowel disease, typically affects the gastrointestinal tract.
- Esophageal involvement in Crohn's disease is uncommon, with only a few reported cases of Crohn's esophagitis.
- Barrett's esophagus is a complication of chronic gastroesophageal reflux disease.
Observation:
- A patient with regional ileitis (Crohn's disease) presented with a benign esophageal stricture.
- The patient had no prior symptoms suggestive of reflux esophagitis.
- Surgical resection of the esophagus revealed features of Crohn's disease and Barrett's esophageal mucosa.
Findings:
- The resected esophagus demonstrated both Crohn's disease and Barrett's esophagus.
- This represents the first reported case of concurrent Crohn's disease and Barrett's esophagus.
- Postoperatively, the patient developed an esophagogastrostomy site fistula.
Implications:
- This case expands the known spectrum of esophageal complications associated with Crohn's disease.
- It suggests that Crohn's disease may predispose to or coexist with Barrett's esophagus.
- Further research is warranted to understand the relationship between inflammatory bowel disease and Barrett's esophagus.