Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Generalized elastolysis (cutis laxa)

R B Harris, M R Heaphy, H O Perry

    The American Journal of Medicine
    |November 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Generalized elastolysis is a rare connective tissue disorder causing elastic fiber fragmentation. This leads to conditions like cutis laxa and aortic aneurysms affecting multiple organ systems.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reducing achievement gaps in undergraduate general chemistry could lift underrepresented students into a "hyperpersistent zone".

    Science advances·2020
    Same author

    Nerve Removal versus Conservative Treatment.

    The American journal of dental science·2019
    Same author

    Student outbreak response teams: lessons learned from a decade of collaboration.

    Public health·2017
    Same author

    Assessing risk factors of sporadic Campylobacter infection: a case-control study in Arizona.

    Epidemiology and infection·2016
    Same author

    Genomic resources notes accepted 1 August 2014-30 September 2014.

    Molecular ecology resources·2014
    Same author

    Impact of a community-based breast cancer screening program on Hopi women.

    Preventive medicine·2011
    Same journal

    GLP-1 Receptor Agonists and Age-related Macular Degeneration Risk in Diabetes or Non-diabetic Obesity: A Retrospective Cohort Study.

    The American journal of medicine·2026
    Same journal

    Marijuana Use and Acute Myocardial Infarction: Mechanistic Insights, Clinical Implications, and Emerging Challenges.

    The American journal of medicine·2026
    Same journal

    Cave Canem - Beware of the Dog.

    The American journal of medicine·2026
    Same journal

    Risk Factors for 30-day Hospital Readmission After Hospital-at-Home Treatment of Acute Pyelonephritis.

    The American journal of medicine·2026
    Same journal

    Mesenteric Panniculitis.

    The American journal of medicine·2026
    Same journal

    Hypercalcemia and hyperferritinemia in a patient with Graves' disease disease.

    The American journal of medicine·2026
    See all related articles

    Area of Science:

    • Connective tissue disorders
    • Biochemistry of connective tissue
    • Systemic diseases

    Background:

    • Generalized elastolysis is a rare systemic disorder affecting connective tissue.
    • Characterized by fragmentation and loss of elastic fibers.
    • Impacts skin, lungs, vasculature, and gastrointestinal tract.

    Observation:

    • Presents three illustrative cases of generalized elastolysis.
    • Reviews an additional 14 cases from existing literature.
    • Highlights typical clinical manifestations across organ systems.

    Findings:

    • Elastic fiber fragmentation, disorganization, and reduction are key pathological features.
    • Associated conditions include cutis laxa, emphysema, aortic aneurysms, and bowel diverticula.

    Related Experiment Videos

  • Etiologic factors involve disruptions in elastic tissue synthesis and degradation.

    • Implications:

    • Understanding the biochemistry of connective tissue is crucial for elucidating disease mechanisms.
    • Further research into elastic tissue synthesis and degradation pathways is warranted.
    • Improved understanding may lead to better diagnostic and therapeutic strategies for connective tissue disorders.