[Pretherapeutical testing of antineoplastic drugs in vitro (author's transl)]

Prediction tests were performed in vitro an organ cultures of different solid human tumors. The effectivity of the antineoplastic drugs was determined by means of the remained 3H-thymidine incorporation into DNA. DNA control values of different tumors (without drug) varying in a very high degree are analyzed and correspond to drug response rate in vitro. The correlation between results of sensitivity tests in vitro and therapeutic effectivity in vivo is discussed.