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Related Concept Videos

Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

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Related Experiment Video

Updated: Jul 25, 2026

A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury
09:24

A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury

Published on: January 5, 2015

The spinal injury learning series: an experimental test

W C Norris, G T Vise, G W Wharton

    Archives of Physical Medicine and Rehabilitation
    |June 1, 1982
    PubMed
    Summary

    The Spinal Injury Learning Series (SILS) improves cognitive and psychomotor skills in patients with spinal cord injuries (SCI). This new technique enhances functional independence and skill retention compared to traditional rehabilitation methods.

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    Published on: June 26, 2019

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    Last Updated: Jul 25, 2026

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    09:24

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    Published on: January 5, 2015

    Assessing Forelimb Function after Unilateral Cervical SCI using Novel Tasks: Limb Step-alternation, Postural Instability and Pasta Handling
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    Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat
    06:44

    Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat

    Published on: June 26, 2019

    Area of Science:

    • Rehabilitation Medicine
    • Neuroscience
    • Patient Education

    Background:

    • Traumatic spinal cord injuries (SCI) require specialized rehabilitation.
    • Current treatments may not fully address cognitive and psychomotor deficits.
    • Behavioral needs of SCI patients are critical for effective recovery.

    Purpose of the Study:

    • To evaluate the effectiveness of the Spinal Injury Learning Series (SILS) for SCI rehabilitation.
    • To compare SILS with traditional rehabilitation methods.
    • To assess improvements in cognitive and psychomotor proficiencies and functional independence.

    Main Methods:

    • A new rehabilitation technique, SILS, was developed, integrating learning and communication strategies.
    • 297 patients with traumatic SCI were enrolled across 6 centers over 29 months.
    • Experimental (SILS) and control (traditional) groups were statistically compared.

    Main Results:

    • SILS group demonstrated higher average cognitive and psychomotor scores one year post-injury.
    • Faster acquisition and better retention of functional independence skills were observed with SILS.
    • While psychomotor independence varied with injury level, SILS showed significant overall effectiveness.

    Conclusions:

    • The Spinal Injury Learning Series (SILS) is a significantly more effective rehabilitation technique than current treatments for SCI.
    • SILS enhances cognitive, psychomotor, and functional independence outcomes in SCI patients.
    • Systematic training incorporating learning and communication methods improves SCI patient recovery.