[Immunomorphologic aspects of sepsis in children under 1-year-old]

Lymphoid system was studied morphologically in 61 infants aged under 1 year dying of sepsis, nonseptic inflammatory diseases and non-inflammatory processes. It was established that in sepsis generalization of the immune response and decompensation of the lymphoid system occurred in the development of which previous disorders of immune responsiveness (thymus pathology, immaturity of the lymphoid system of premature babies, respiratory viral infections) are of great importance. Unlike sepsis, local inflammatory processes are characterized predominantly by limited immune reaction and decompensation of lymphoid system has a local character. In babies of the first month of age reactions of the T-lymphocyte system predominate, in older babies those of the B-lymphocyte system.