Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mitral valve replacement after closed mitral commissurotomy

R Rutledge, C L McIntosh, A G Morrow

    Circulation
    |August 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Bacterial endocarditis following aortic valve replacement. Clinical and pathologic correlations.

    Circulation·2015
    Same author

    The assessment of operative results in congenital heart disease by intraoperative indicator-dilution curves.

    Circulation·2015
    Same author

    CARDIOVASCULAR SURGERY.

    A listing of research in the cardiovascular field·2014
    Same author

    An evaluation of the Guterman pregnancy test.

    American journal of obstetrics and gynecology·2010
    Same author

    Planned neck dissection for advanced primary head and neck malignancy treated with organ preservation therapy: disease control and survival outcomes.

    Head & neck·2001
    Same author

    The Society of Thoracic Surgeons National Congenital Heart Surgery Database Report: analysis of the first harvest (1994-1997).

    The Annals of thoracic surgery·1999

    Closed mitral commissurotomy (CMC) significantly improved mitral stenosis symptoms and survival in 303 patients. Mitral valve replacement (MVR) was needed for some, but also provided significant long-term benefits.

    Area of Science:

    • Cardiology
    • Cardiac Surgery
    • Valvular Heart Disease

    Background:

    • Acquired isolated mitral stenosis is a significant valvular heart disease.
    • Closed mitral commissurotomy (CMC) has been a historical treatment option.
    • Long-term outcomes and predictors of reintervention after CMC require evaluation.

    Purpose of the Study:

    • To evaluate the long-term efficacy and outcomes of closed mitral commissurotomy (CMC) for acquired isolated mitral stenosis.
    • To identify factors associated with the need for subsequent mitral valve replacement (MVR).
    • To assess the outcomes of MVR in patients who previously underwent CMC.

    Main Methods:

    • Retrospective analysis of 303 patients who underwent CMC between 1954 and 1980.
    • Assessment of hemodynamic parameters (mitral valve gradient, valve area index) and functional class before and after CMC.

    Related Experiment Videos

  • Actuarial survival analysis and identification of predictors for late MVR.

    • Main Results:

    • CMC significantly reduced mitral valve gradient and increased valve area index (p < 0.001).
    • 92% of patients improved functional class post-CMC, with 5, 10, and 15-year survival rates of 95%, 82%, and 70%.
    • 18% of patients required MVR due to restenosis or residual stenosis; MVR also provided significant clinical improvement and survival benefits.

    Conclusions:

    • Closed mitral commissurotomy (CMC) offers excellent long-term hemodynamic and clinical benefits for selected patients with mitral stenosis.
    • Preoperative and early postoperative factors predict the need for late mitral valve replacement (MVR).
    • Mitral valve replacement (MVR) is an effective option for patients experiencing symptomatic deterioration after CMC.