Related Experiment Videos
Problems and complications in the adolescent with sickle cell disease
The American Journal of Pediatric Hematology/Oncology
|January 1, 1982
Summary
Adolescents with sickle cell disease (SCD) experience a seemingly calm period, but face significant growth and maturation issues. This review highlights key complications during their second decade of life.
Area of Science:
- Hematology
- Pediatrics
- Adolescent Medicine
Background:
- Adolescence in sickle cell disease (SCD) is often perceived as a medically stable period.
- However, literature suggests a significant link between SCD and impaired growth and sexual maturation.
- This phase presents unique challenges for patients with SCD.
Purpose of the Study:
- To review the spectrum of medical issues in adolescents with SCD.
- To highlight complications occurring during the second decade of life for SCD patients.
- To discuss the relationship between SCD and developmental delays.
Main Methods:
- Review of recent medical literature on SCD in adolescents.
- Presentation of a retrospective series of 76 SCD cases.
- Analysis of complications during the second decade of life.
Main Results:
- Growth and sexual maturation retardation are significantly associated with SCD, independent of disease severity.
- Common complications include psychological disturbances, leg ulcers, aseptic necrosis, pulmonary disease, priapism, stroke, and cholelithiasis.
- The study aims to clarify the actual disease spectrum in this age group.
Conclusions:
- Adolescence in SCD, while seemingly calm, involves significant medical and developmental challenges.
- Understanding these complications is crucial for comprehensive patient care.
- Further prospective studies are needed to fully delineate the disease course.