Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Auditory brain stem responses in infantile spasms

K Kaga, R R Marsh, Y Fukuyama

    International Journal of Pediatric Otorhinolaryngology
    |March 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Auditory Brain Stem Responses Recorded With Uncushioned Earphones.

    American journal of audiology·2015
    Same author

    Secondary, profound, sensorineural hearing loss after recovery from haemolytic uraemic syndrome due to enterohaemorrhagic Escherichia coli, and subsequent cochlear implantation, in two Japanese children.

    The Journal of laryngology and otology·2013
    Same author

    A prevalent founder mutation and genotype-phenotype correlations of OTOF in Japanese patients with auditory neuropathy.

    Clinical genetics·2012
    Same author

    Biglycan is a specific marker and an autocrine angiogenic factor of tumour endothelial cells.

    British journal of cancer·2012
    Same author

    Arachnoid cysts confined to the internal auditory canal or facial nerve canal.

    The Journal of laryngology and otology·2011
    Same author

    Histopathological differences in bony destruction of malleus and incus following mastoidectomy.

    The Journal of laryngology and otology·2010
    Same journal

    Postoperative complications after injection laryngoplasty for minor laryngeal clefts.

    International journal of pediatric otorhinolaryngology·2026
    Same journal

    Tranexamic acid and beyond: A systematic review of pediatric post-tonsillectomy hemorrhage protocols and introduction of a universal management guideline.

    International journal of pediatric otorhinolaryngology·2026
    Same journal

    Percutaneous contralateral vocal fold lateralization in pediatric bilateral vocal fold paralysis.

    International journal of pediatric otorhinolaryngology·2026
    Same journal

    Outcomes of single-stage excision in infected preauricular sinus: a retrospective cohort study.

    International journal of pediatric otorhinolaryngology·2026
    Same journal

    Therapy changes in the treatment of subglottic laryngitis: A 30-year experience in Croatia.

    International journal of pediatric otorhinolaryngology·2026
    Same journal

    Regional barriers and innovative solutions in the medical rehabilitation of children with cochlear implants in Uzbekistan: A telemonitored home-based versus center-based comparative study.

    International journal of pediatric otorhinolaryngology·2026
    See all related articles

    Infants with infantile spasms often have auditory brain stem evoked responses (ABRs) abnormalities, indicating brain stem involvement. This, along with psychomotor retardation, explains their poor response to sound.

    Area of Science:

    • Neuroscience
    • Audiology
    • Pediatrics

    Background:

    • Infantile spasms are associated with neurological dysfunction.
    • Infants with infantile spasms often exhibit inattention to auditory stimuli.
    • The precise level of auditory pathway lesion in these infants is not well understood.

    Purpose of the Study:

    • To investigate auditory brain stem evoked responses (ABRs) and behavioral thresholds in infants with infantile spasms.
    • To determine the site of auditory pathway dysfunction in infants experiencing infantile spasms.
    • To correlate auditory findings with psychomotor status.

    Main Methods:

    • Auditory brain stem evoked responses (ABRs) were measured, including thresholds, wave latencies, and interval latencies.
    • Behavioral audiometric thresholds were assessed using conditioned-orientation-reflex (COR) audiometry.

    Related Experiment Videos

  • ABR data were compared to age-matched controls.

    • Main Results:

    • Thirty percent of infants with infantile spasms displayed abnormal ABRs compared to controls.
    • ABR abnormalities included wave disappearance, prolonged V-I interval, and absent responses, indicating brain stem dysfunction.
    • Eighty-six percent of patients had elevated behavioral thresholds, suggesting cortical dysfunction due to psychomotor retardation, not peripheral hearing loss.

    Conclusions:

    • Brain stem involvement is a significant finding in infants with infantile spasms.
    • Auditory inattention in these infants is primarily linked to psychomotor retardation and associated cortical dysfunction.
    • ABR testing is crucial for identifying central auditory pathway lesions in infantile spasms.