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Related Experiment Videos

The urinary sediment in hydronephrosis

A Wahlin

    Acta Medica Scandinavica
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Phase contrast microscopy revealed few casts in hydronephrosis patients. Histiocyte-like cells were common, especially without bacteriuria, suggesting their role in urinary tract conditions.

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    Area of Science:

    • Urology
    • Pathology
    • Microscopy

    Background:

    • Hydronephrosis diagnosis often involves urinalysis.
    • Microscopic examination of urinary sediment is crucial for identifying cellular components and casts.
    • Understanding cellular morphology in urinary sediments aids in diagnosing various renal and urinary tract conditions.

    Purpose of the Study:

    • To investigate the cellular composition of urinary sediments in patients with hydronephrosis using phase contrast microscopy.
    • To correlate the presence and proportion of specific cell types with clinical findings such as bacteriuria, catheterization, calculi, and diabetes.

    Main Methods:

    • Phase contrast microscopy was employed for the microscopic examination of urinary sediments.
    • Differential cell counts were performed on samples from 19 patients diagnosed with hydronephrosis.

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  • Clinical data including the presence of catheter, calculi, diabetes, and bacteriuria were collected for correlation.

    • Main Results:

    • Casts were infrequently observed in the urinary sediments of hydronephrosis patients.
    • Elevated erythrocyte counts were associated with catheter use, urinary calculi, or diabetes.
    • Increased leukocyte counts were primarily observed in patients with bacteriuria.
    • A significant proportion (64%) of histiocyte-like cells were found in 6 out of 12 cases undergoing differential counts.
    • Cases with bacteriuria or a history of urinary tract infection showed a lower proportion (14%) of histiocyte-like cells.

    Conclusions:

    • Phase contrast microscopy is valuable for analyzing urinary sediments in hydronephrosis.
    • Histiocyte-like cells appear to be a prominent feature in hydronephrosis sediments, particularly in the absence of active infection.
    • The findings suggest a potential role for histiocytes in the pathophysiology of hydronephrosis or related urinary tract conditions.