Epinephrine-enhanced renal angiography in renal mass lesions: is it worth performing?

In our experience, properly performed epinephrine-enhanced angiography is a useful technique to improve accuracy in the angiographic diagnosis of renal masses. This pharmacologic enhancement is helpful in establishing the benignity of some lesions, clearly establishing malignancy in those questionable by routine angiography, and actually detecting malignant lesions not seen at all on unenhanced angiograms. Six examples of these situations are illustrated. The basic principles and pitfalls in the performance of the technique as well as its limitations are discussed.