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Updated: May 1, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

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Higher order metaphase chromosome structure: evidence for metalloprotein interactions

C D Lewis, U K Laemmli

    Cell
    |May 1, 1982
    PubMed
    Summary

    DNA organization in metaphase chromosomes relies on metalloprotein interactions for scaffolding. Copper ions (Cu2+) specifically stabilize these structures, revealing key scaffolding proteins Sc1 and Sc2.

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