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Auditory brainstem response abnormalities in adductor spasmodic dysphonia

T Finitzo-Hieber, F J Freeman, I J Gerling

    American Journal of Otolaryngology
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

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    Adductor spasmodic dysphonia may involve brainstem dysfunction. Auditory brainstem response tests revealed impaired nerve signal conduction in most patients, suggesting a central nervous system abnormality.

    Area of Science:

    • Neurology
    • Otolaryngology
    • Neuroscience

    Background:

    • Adductor spasmodic dysphonia (ADSD) is a focal dystonia affecting laryngeal muscles.
    • The underlying pathophysiology of ADSD remains incompletely understood.
    • Central nervous system involvement has been hypothesized but not definitively established.

    Purpose of the Study:

    • To investigate potential brainstem dysfunction in patients with ADSD.
    • To utilize auditory brainstem response (ABR) as a diagnostic tool for central nervous system abnormalities in ADSD.

    Main Methods:

    • Auditory brainstem response (ABR) testing was performed on six patients diagnosed with ADSD.
    • ABR was used to assess the integrity and speed of neural impulse conduction through the auditory pathway.

    Related Experiment Videos

  • High stimulus repetition rates were employed to evaluate the brainstem's capacity to handle rapid signal processing.

    • Main Results:

    • Five out of six patients exhibited compromised auditory brainstem auditory pathway function.
    • Four patients showed significantly increased wave V latencies at high stimulus repetition rates, exceeding normative values.
    • One patient presented with prolonged interpeak latencies, consistent with previous findings.

    Conclusions:

    • The findings suggest a central nervous system abnormality, specifically within the brainstem, in individuals with ADSD.
    • ABR testing can reveal objective evidence of brainstem dysfunction in ADSD patients.
    • These results support the hypothesis that ADSD may stem from neurological underpinnings rather than solely peripheral laryngeal issues.