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Fever in multiple myeloma
Israel Journal of Medical Sciences
|August 1, 1982
Abstract:
Tumor-associated fever is a rare manifestation of multiple myeloma (MM). Two patients with MM are described, in whom this disease was associated with a fulminant course and resistance to therapy. The patients had none of the currently recognized "poor prognostic factors" of MM. Thus it is suggested that tumor-associated fever should be considered to be an indicator of poor prognosis in MM.
Insights
Tumor-associated fever is a rare sign of multiple myeloma (MM). This fever may indicate a poor prognosis, even without other known risk factors, suggesting it should be considered in MM patient assessment.
Area of Science:
- Oncology
- Hematology
- Internal Medicine
Background:
- Multiple myeloma (MM) is a hematologic malignancy.
- Tumor-associated fever is an uncommon manifestation of MM.
Observation:
- Two cases of MM presented with tumor-associated fever.
- These patients experienced aggressive disease progression and treatment resistance.
Findings:
- The patients lacked established poor prognostic factors for MM.
- Tumor-associated fever was identified as a potential indicator of poor prognosis.
Implications:
- Tumor-associated fever may signify a more aggressive MM subtype.
- Consideration of fever as a prognostic marker could refine MM patient management.
- Further research is warranted to validate fever as a prognostic indicator in MM.