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Related Experiment Videos

Cone biopsy during pregnancy

E V Hannigan, H H Whitehouse, W D Atkinson

    Obstetrics and Gynecology
    |October 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Cervical conization in pregnant women with abnormal Papanicolaou smears led to significant morbidity and perinatal mortality. This study highlights the risks associated with this diagnostic approach for abnormal cervical screening during pregnancy.

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    Area of Science:

    • Gynecologic Oncology
    • Perinatal Medicine
    • Cervical Pathology

    Background:

    • Abnormal Papanicolaou smears in pregnancy necessitate careful diagnostic evaluation.
    • Historically, cervical conization was liberally used for diagnosis in pregnant patients.
    • Concerns exist regarding the safety and efficacy of invasive procedures during pregnancy.

    Purpose of the Study:

    • To evaluate the outcomes of cervical conization in pregnant patients with abnormal Papanicolaou smears.
    • To assess the diagnostic yield and associated morbidity of this procedure.
    • To inform changes in diagnostic protocols for pregnant women with cervical abnormalities.

    Main Methods:

    • Retrospective review of 82 pregnant patients who underwent cervical conization.

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  • Analysis of diagnostic findings, including invasive carcinoma detection.
  • Assessment of procedure-related morbidity and perinatal mortality.

    • Main Results:

    • Fifteen patients experienced significant morbidity, primarily cervical bleeding.
    • Uncorrected perinatal mortality was 44.1 per 1000 births.
    • Invasive cervical carcinoma was diagnosed in several cases, with varying detection methods (cone biopsy, colposcopically directed punch biopsy).

    Conclusions:

    • Liberal use of cervical conization in pregnant women with abnormal Papanicolaou smears is associated with considerable morbidity and perinatal risks.
    • The diagnostic schema has been revised to reduce the frequency of biopsies in pregnant patients.
    • A less invasive approach is recommended for evaluating cervical abnormalities during pregnancy.