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Related Experiment Videos

A sampling and analytical procedure for skin-contamination evaluation

R R Keenan, S B Cole

    American Industrial Hygiene Association Journal
    |July 1, 1982
    PubMed
    Summary
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    A new method effectively samples and analyzes skin contamination from liquified coal products using cyclohexane and UV fluorescence. This technique offers high recovery rates and a low detection limit for heavy distillate fuel oil.

    Area of Science:

    • Environmental Science
    • Analytical Chemistry
    • Occupational Health

    Background:

    • Skin contamination with liquified coal products poses health risks.
    • Accurate assessment of dermal exposure is crucial for risk management.
    • Existing methods for evaluating skin contamination may be limited.

    Purpose of the Study:

    • To develop and validate a sampling and analytical procedure for assessing skin contamination by liquified coal products.
    • To establish a reliable method for quantifying exposure levels on the skin.

    Main Methods:

    • A procedure involving spraying cyclohexane (10 mL) onto a 5 cm2 skin area.
    • Collection of rinsings into a 12-mL glass vial for analysis.
    • Analysis of contaminants using UV fluorescence spectroscopy.

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    Main Results:

    • Achieved high recovery rates exceeding 95% in preliminary studies.
    • Established a low limit of detection of 0.2 microgram for heavy distillate fuel oil.
    • Demonstrated the potential applicability to other skin contaminants with appropriate solvent and analytical methods.

    Conclusions:

    • The developed procedure provides an effective means to evaluate skin contamination with liquified coal products.
    • The method is sensitive and accurate, with potential for broader application in toxicology and environmental monitoring.