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[Intracranial tuberculoma: clinical and pathological aspects]
Arquivos De Neuro-Psiquiatria
|June 1, 1982
Summary
Intracranial tuberculomas are rare, accounting for 4.2% of brain lesions. These tumors, often found in young patients, present symptoms similar to other space-occupying brain lesions.
Area of Science:
- Neurology
- Pathology
- Infectious Diseases
Background:
- Tuberculomas are granulomatous lesions caused by Mycobacterium tuberculosis.
- Intracranial tuberculomas are a rare manifestation of disseminated tuberculosis.
Purpose of the Study:
- To analyze the incidence, location, and clinical presentation of intracranial tuberculomas.
Main Methods:
- Retrospective analysis of 19,760 autopsies and 72,972 biopsies over 41 years.
- Identification and characterization of 24 intracranial tuberculomas in 17 patients.
Main Results:
- Intracranial tuberculomas represented 4.2% of space-occupying lesions.
- Most lesions were in the cerebral hemispheres; one-third were in the cerebellum.
- Two-thirds of affected patients were under 20 years old.
- Clinical presentation mimicked other intracranial space-occupying lesions, including signs of raised intracranial pressure.
Conclusions:
- Intracranial tuberculomas are uncommon but significant intracranial space-occupying lesions.
- Pediatric and young adult populations are predominantly affected.
- Early diagnosis and treatment are crucial due to non-specific clinical presentations.