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Updated: Aug 19, 2026

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs
Published on: May 21, 2019
[Oxygen tension in different organs and tissues and hemodynamic indices during tourniquet shock]
Abstract:
Experiments were made on 160 rats to examine the time course of changes in oxygen tension (pO2) in different organs and tissues during tourniquet shock. It was ascertained that pO2 in the liver was reduced before the tourniquets were removed from the limbs, in the presence of normal characteristics of the central and systemic hemodynamics. After circulation in the limbs was resumed following 6 hours of ischemia, pO2 in the liver and kidneys was reduced, respectively, to 26.8 and 48.6% of normal for 4 hours. It was disclosed that these changes preceded the shifts in circulation. pO2 in the small intestine, skin and muscles also fell to 97, 80.8 and 79.4%, respectively, within the same period of time. Oxygen tension in the cerebral cortex remained high within all the periods of tourniquet shock. pO2 fall in the cerebral cortex was seen only in the agonal period in the presence of deep disorders in circulation and respiration.
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