Hypertensive choroidopathy

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Updated: Oct 16, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
07:00

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

Published on: August 14, 2013

T T McMahon, J H Maino

    Journal of the American Optometric Association
    |September 1, 1982
    PubMed

    Insights

    Hypertension affects eye circulation, causing choroidal changes that are more severe in malignant hypertension. These hypertensive choroidopathies, including Siegrist and Elschnig spots, offer vital prognostic information for patient survival.

    Area of Science:

    • Ophthalmology
    • Cardiovascular Medicine
    • Pathology

    Background:

    • Hypertension significantly impacts ocular structures, affecting both retinal and choroidal blood flow.
    • Understanding these vascular changes is crucial for diagnosing and managing hypertensive eye disease.

    Observation:

    • Clinical and pathological studies reveal choroidal alterations in both benign and malignant hypertension.
    • These changes are markedly more pronounced in cases of malignant hypertension.

    Findings:

    • Specific lesions, such as Siegrist and Elschnig spots, are characteristic manifestations of hypertensive choroidopathy.
    • The presence and severity of these choroidal changes correlate with the stage of hypertension.

    Implications:

    • Hypertensive choroidopathy serves as a critical indicator of systemic vascular health.
    • Clinical evidence of these changes holds significant prognostic value for patient longevity and overall health outcomes.

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