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Related Experiment Videos

[Cogan-Reese syndrome]

B Daicker, G Sturrock, R Guggenheim

    Klinische Monatsblatter Fur Augenheilkunde
    |June 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Cogan-Reese syndrome, characterized by iris nodules, is linked to endothelialization, a finding that may explain late diagnosis. This condition is now considered part of the irido-corneal-endothelial syndromes.

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    Area of Science:

    • Ophthalmology
    • Pathology

    Background:

    • Presents a case of Cogan-Reese syndrome (iris nevus) with detailed clinical, histological, and ultrastructural findings.
    • Highlights the late onset of iris nodules, appearing 14 years after juvenile open-angle glaucoma diagnosis.

    Observation:

    • Details the failure of glaucoma treatment due to endothelialization of surgical blebs.
    • Describes novel findings of endothelialization and Descemet's membrane deposition on the lens and zonule.

    Findings:

    • Histological evidence suggests peripheral anterior synechiae and iris nodules are secondary to endothelialization.
    • Cytological similarities link Cogan-Reese syndrome to Chandler syndrome and the irido-corneal-endothelial group.

    Implications:

    Related Experiment Videos

  • The findings suggest Cogan-Reese syndrome may be diagnosed late due to its secondary nature.
  • Supports the classification of Cogan-Reese syndrome within the spectrum of irido-corneal-endothelial syndromes.