[Blood lipid changes in rats in hypoxia]

Changes in the total lipid spectrum of serum of rats exposed to acute hypoxia were examined. Quantitative measurements of lipids showed a decrease of total lipids and a redistribution of lipid components in absolute and relative values. A distinct decrease in the quantity of cholesterol ester and a concomitant increase of free cholesterol, an elevation in the relative content of free fatty acids and emergence of diglycerides were noted. The qualitative composition of phospholipids remained unaltered, whereas the absolute amount of glycerophosphates, lysoforms of phosphatids, phosphatid acids and lecithin fraction increased. The changes in the ratio of lipid components are closely connected with the qualitative and quantitative changes in the composition of serum lipoproteins.