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Bone mineral and intestinal calcium absorption after partial gastrectomy
Scandinavian Journal of Gastroenterology
|April 1, 1982
Summary
Partial gastrectomy for benign ulcers did not significantly affect bone mineral density or calcium absorption in patients 3-4 years post-surgery. Some biochemical markers showed minor changes, but overall bone health remained comparable to controls.
Area of Science:
- Gastroenterology
- Bone Metabolism
- Surgical Outcomes
Background:
- Partial gastrectomy is a surgical procedure for benign ulcer disease.
- Long-term effects on bone metabolism and mineral absorption require investigation.
Purpose of the Study:
- To assess bone mineral density and radiocalcium absorption in patients after partial gastrectomy.
- To evaluate long-term biochemical and physiological changes following this surgery.
Main Methods:
- Compared 50 partial gastrectomy patients with controls 3-4 years post-surgery.
- Measured bone mineral density, serum/urine minerals, fecal fat, and radiocalcium (47Ca) absorption.
- Utilized 241Am gamma ray attenuation for bone density assessment.
Main Results:
- Serum alkaline phosphatase increased; serum inorganic phosphorus and urinary calcium decreased.
- No significant differences in bone mineral density between patients and controls.
- Intestinal 47Ca absorption was similar in both groups.
Conclusions:
- Partial gastrectomy for benign ulcers does not appear to compromise bone mineral density or intestinal calcium absorption long-term.
- Minor biochemical alterations observed do not translate to significant bone health deficits.