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Related Experiment Videos

Non--cloth-covered caged-ball prostheses. The second decade

Q Macmanus, G L Grunkemeier, L E Lambert

    The Journal of Thoracic and Cardiovascular Surgery
    |December 1, 1978
    PubMed
    Summary

    The Starr-Edwards caged-ball heart valves demonstrate excellent long-term durability and survival rates, offering a reliable option for aortic and mitral valve replacement with low structural failure.

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    CARDIOVASCULAR SURGERY.

    A listing of research in the cardiovascular field·2014

    Area of Science:

    • Cardiovascular Surgery
    • Biomedical Engineering
    • Prosthetic Devices

    Background:

    • The Starr-Edwards Models 6120 (mitral) and 1200/60 (aortic) are caged-ball heart valve prostheses.
    • These valves, introduced in 1965, feature cloth-covered sewing rings and bare-metal struts.
    • They represent the longest-serving heart valve prostheses in continuous clinical use.

    Purpose of the Study:

    • To analyze and compare the late clinical results of Starr-Edwards caged-ball valves with newer prostheses.
    • To evaluate the long-term durability, survival, and complication rates of these specific valve models.

    Main Methods:

    • Retrospective analysis of 134 mitral (6120) and 282 aortic (1200/60) valve replacements performed between 1965 and 1977.
    • Follow-up of operative survivors for a mean of 5.4 years (mitral) and 4.3 years (aortic).

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  • Assessment of survival rates, valve-related deaths, embolic events, structural failures, and functional class.

    • Main Results:

    • Twelve-year survival rates were 50% for mitral and 61% for aortic valves.
    • At 12 years, 88% of mitral valves and 92% of aortic valves remained in situ (removal-free rate).
    • Embolic rates were 5.8% (all) and 2.2% (serious) per patient-year for mitral, and 5.0% (all) and 1.8% (serious) for aortic valves. No structural failures (ball variance) were observed.

    Conclusions:

    • Starr-Edwards caged-ball valves exhibit unquestionable durability and well-documented results into their second decade.
    • These prostheses offer a valid, current choice for aortic and mitral valve replacement, providing a benchmark for comparison.
    • Ninety percent of 10-year survivors were in NYHA Functional Class I or II, indicating good functional status.