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Left atrial myxoma simulating peripheral vasculitis

K A Huston, J J Combs, J T Lie

    Mayo Clinic Proceedings
    |November 1, 1978
    PubMed
    Summary
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    Left atrial myxoma presents diagnostic challenges. This case highlights unusual neurological and arterial symptoms preceding diagnosis, emphasizing the need for broader clinical suspicion.

    Area of Science:

    • Cardiology
    • Neurology
    • Pathology

    Background:

    • Left atrial myxoma is a rare cardiac tumor.
    • Clinical diagnosis can be challenging due to varied presentations.

    Observation:

    • This case presented with unusual neurological and peripheral arterial symptoms.
    • Histologic findings revealed myxomatous emboli and vasculitis in peripheral arteries.
    • These signs preceded the echocardiographic diagnosis of left atrial myxoma by 14 months.

    Findings:

    • The patient exhibited peripheral arterial myxomatous emboli.
    • Vasculitis was present, but without clear immunologic evidence of collagen vascular disease.
    • Left atrial myxoma was eventually diagnosed via echocardiography.

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    Implications:

    • Recognizing the enigmatic and variable clinical presentations of left atrial myxoma is crucial.
    • Early suspicion based on diverse symptoms can improve diagnostic timelines.
    • This case underscores the importance of considering cardiac tumors in patients with unexplained embolic phenomena.