[Effect of chronic exposure to carbon monoxide on the biochemical composition of human blood]

Protein, lipid and carbohydrate metabolism of men was investigated during their prolonged exposure to a closed atmosphere containing carbon monoxide at a concentration of 20-10 mg/m3. A 30-day exposure of test subjects to carbon monoxide at a concentration of 20-15 mg/m3 caused an increase of albumin, beta-globulins, total lipids, cholesterol, beta-lipoproteins in the serum and a decrease of the sugar concentration in the blood. A 90-day exposure of test subjects to carbon monoxide at a concentration of 10 mg/m3 did not bring about significant changes in the above parameters. The provocative test for glucose tolerance showed no changes in the glycaemic regulation.