Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exposure to formaldehyde: effects on pulmonary function

R Alexandersson, G Hedenstierna, B Kolmodin-Hedman

    Archives of Environmental Health
    |September 1, 1982
    PubMed
    Summary

    Formaldehyde exposure in carpentry shops caused respiratory symptoms and reduced lung function. This study highlights the occupational health risks associated with formaldehyde, indicating potential bronchoconstriction in exposed workers.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial.

    JAMA·2019
    Same author

    Tidal changes in PaO<sub>2</sub> and their relationship to cyclical lung recruitment/derecruitment in a porcine lung injury model.

    British journal of anaesthesia·2019
    Same author

    Specific anesthesia-induced lung volume changes from induction to emergence: a pilot study.

    Acta anaesthesiologica Scandinavica·2017
    Same author

    Atelectasis is inversely proportional to transpulmonary pressure during weaning from ventilator support in a large animal model.

    Acta anaesthesiologica Scandinavica·2017
    Same author

    Erratum to Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial.

    Trials·2017
    Same author

    Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial.

    Trials·2017

    Area of Science:

    • Occupational Health
    • Environmental Medicine
    • Pulmonary Medicine

    Background:

    • Formaldehyde is a common chemical irritant found in various industrial settings, including carpentry shops.
    • Previous studies suggest potential respiratory effects of formaldehyde exposure, but further investigation into specific pulmonary function changes is warranted.

    Purpose of the Study:

    • To investigate the effects of occupational formaldehyde exposure on respiratory symptoms and pulmonary function in carpentry shop workers.
    • To assess changes in spirometry and lung function parameters following a workday with formaldehyde exposure.

    Main Methods:

    • A comparative study involving 47 formaldehyde-exposed workers and 20 unexposed controls from a carpentry shop.
    • Pulmonary function tests, including spirometry and single breath nitrogen washout, were conducted before and after a workday.
    • Symptom questionnaires were administered to assess respiratory and eye irritation.

    Main Results:

    • Exposed subjects reported significantly more eye, throat, and chest oppression symptoms compared to controls.
    • Pulmonary function tests revealed a significant reduction in forced expiratory volume in 1 second (FEV1), percent forced expiratory volume (FEV%), and maximum midexpiratory flow (MMEF) after formaldehyde exposure.
    • An increase in closing volume as a percentage of vital capacity was observed, suggesting bronchoconstriction.
    • Smokers and non-smokers showed similar pulmonary function changes.

    Conclusions:

    • Occupational exposure to formaldehyde at mean concentrations of 0.45 mg/m3 in carpentry shops is associated with increased respiratory symptoms and acute, reversible bronchoconstriction.
    • The findings underscore the need for effective control measures to minimize formaldehyde exposure in the workplace to protect worker respiratory health.

    Related Experiment Videos